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human melanocytes cell line (hem)  (BioVector Inc)

 
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    BioVector Inc human melanocytes cell line (hem)
    Human Melanocytes Cell Line (Hem), supplied by BioVector Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/human melanocytes cell line (hem)/product/BioVector Inc
    Average 90 stars, based on 1 article reviews
    human melanocytes cell line (hem) - by Bioz Stars, 2026-03
    90/100 stars

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    Human epidermal <t>melanocytes</t> <t>HEM</t> and human primary melanoma MM418-C1 monolayer 24 h after being exposed to 1000 Gy 90 kVp SBB (width 500 µm). Both cell types are treated with 1 m M AuNPs. The boundaries of the radiation fields are marked with orange lines. (A1) HEM immediately after exposure, (A2) 24 h, (A3) 48 h and (A4) 96 h after exposure. (B1) MM418-C1 immediately after exposure, (B1) 24 h, (B2) 48 h and (B4) 96 h after exposure.
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    Human epidermal <t>melanocytes</t> <t>HEM</t> and human primary melanoma MM418-C1 monolayer 24 h after being exposed to 1000 Gy 90 kVp SBB (width 500 µm). Both cell types are treated with 1 m M AuNPs. The boundaries of the radiation fields are marked with orange lines. (A1) HEM immediately after exposure, (A2) 24 h, (A3) 48 h and (A4) 96 h after exposure. (B1) MM418-C1 immediately after exposure, (B1) 24 h, (B2) 48 h and (B4) 96 h after exposure.
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    Figure 1. PLCB2 expression in malignant melanoma cell lines. (A) The heatmap analysis was performed by R software with wilcoxTest package (P<0.05 and log2 fold change >1) to illustrate miRNA expression profiles in the GEO database (GSE38290). (B) Volcano plot of DEGs. DEGs with log2 fold change >1.5 are shown in red. GSEA analysis was performed by Broad Institute website to show significantly enriched gene sets in melanoma mainly enriched in (C) cell growth, (D) regula- tion of MAPK cascade and (E) pathways in cancer. (F) The diagram of the PPI network. Co‑expression network of 11 genes. (G) Core protein histogram. The vertical coordinates are the gene names, and the horizontal coordinates are the number of adjacent genes, and the height represents the number of line connected genes. (H) mRNA expression level of PLCB2 in human melanoma cell lines was detected by RT‑PCR. GAPDH was used as a load control. Data are presented as the mean ± standard deviation. **P<0.01 vs. the <t>NHEM</t> cell group. PLCB2, phospholipase C β2; DEGs, differentially expressed genes; PPI‑protein‑protein interaction.
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    Figure 1. PLCB2 expression in malignant melanoma cell lines. (A) The heatmap analysis was performed by R software with wilcoxTest package (P<0.05 and log2 fold change >1) to illustrate miRNA expression profiles in the GEO database (GSE38290). (B) Volcano plot of DEGs. DEGs with log2 fold change >1.5 are shown in red. GSEA analysis was performed by Broad Institute website to show significantly enriched gene sets in melanoma mainly enriched in (C) cell growth, (D) regula- tion of MAPK cascade and (E) pathways in cancer. (F) The diagram of the PPI network. Co‑expression network of 11 genes. (G) Core protein histogram. The vertical coordinates are the gene names, and the horizontal coordinates are the number of adjacent genes, and the height represents the number of line connected genes. (H) mRNA expression level of PLCB2 in human melanoma cell lines was detected by RT‑PCR. GAPDH was used as a load control. Data are presented as the mean ± standard deviation. **P<0.01 vs. the <t>NHEM</t> cell group. PLCB2, phospholipase C β2; DEGs, differentially expressed genes; PPI‑protein‑protein interaction.
    Hem Cell Line, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Figure 1. PLCB2 expression in malignant melanoma cell lines. (A) The heatmap analysis was performed by R software with wilcoxTest package (P<0.05 and log2 fold change >1) to illustrate miRNA expression profiles in the GEO database (GSE38290). (B) Volcano plot of DEGs. DEGs with log2 fold change >1.5 are shown in red. GSEA analysis was performed by Broad Institute website to show significantly enriched gene sets in melanoma mainly enriched in (C) cell growth, (D) regula- tion of MAPK cascade and (E) pathways in cancer. (F) The diagram of the PPI network. Co‑expression network of 11 genes. (G) Core protein histogram. The vertical coordinates are the gene names, and the horizontal coordinates are the number of adjacent genes, and the height represents the number of line connected genes. (H) mRNA expression level of PLCB2 in human melanoma cell lines was detected by RT‑PCR. GAPDH was used as a load control. Data are presented as the mean ± standard deviation. **P<0.01 vs. the <t>NHEM</t> cell group. PLCB2, phospholipase C β2; DEGs, differentially expressed genes; PPI‑protein‑protein interaction.
    Normal Human Epidermal Melanocyte Primary Cell Line Hem A, supplied by ScienCell, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Figure 1. PLCB2 expression in malignant melanoma cell lines. (A) The heatmap analysis was performed by R software with wilcoxTest package (P<0.05 and log2 fold change >1) to illustrate miRNA expression profiles in the GEO database (GSE38290). (B) Volcano plot of DEGs. DEGs with log2 fold change >1.5 are shown in red. GSEA analysis was performed by Broad Institute website to show significantly enriched gene sets in melanoma mainly enriched in (C) cell growth, (D) regula- tion of MAPK cascade and (E) pathways in cancer. (F) The diagram of the PPI network. Co‑expression network of 11 genes. (G) Core protein histogram. The vertical coordinates are the gene names, and the horizontal coordinates are the number of adjacent genes, and the height represents the number of line connected genes. (H) mRNA expression level of PLCB2 in human melanoma cell lines was detected by RT‑PCR. GAPDH was used as a load control. Data are presented as the mean ± standard deviation. **P<0.01 vs. the <t>NHEM</t> cell group. PLCB2, phospholipase C β2; DEGs, differentially expressed genes; PPI‑protein‑protein interaction.
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    human melanocytes cell line (hem) - by Bioz Stars, 2026-03
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    Figure 1. PLCB2 expression in malignant melanoma cell lines. (A) The heatmap analysis was performed by R software with wilcoxTest package (P<0.05 and log2 fold change >1) to illustrate miRNA expression profiles in the GEO database (GSE38290). (B) Volcano plot of DEGs. DEGs with log2 fold change >1.5 are shown in red. GSEA analysis was performed by Broad Institute website to show significantly enriched gene sets in melanoma mainly enriched in (C) cell growth, (D) regula- tion of MAPK cascade and (E) pathways in cancer. (F) The diagram of the PPI network. Co‑expression network of 11 genes. (G) Core protein histogram. The vertical coordinates are the gene names, and the horizontal coordinates are the number of adjacent genes, and the height represents the number of line connected genes. (H) mRNA expression level of PLCB2 in human melanoma cell lines was detected by RT‑PCR. GAPDH was used as a load control. Data are presented as the mean ± standard deviation. **P<0.01 vs. the <t>NHEM</t> cell group. PLCB2, phospholipase C β2; DEGs, differentially expressed genes; PPI‑protein‑protein interaction.
    Normal Epidermal Melanocytes Cell Line Hem, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/normal epidermal melanocytes cell line hem/product/ATCC
    Average 99 stars, based on 1 article reviews
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    Figure 1. PLCB2 expression in malignant melanoma cell lines. (A) The heatmap analysis was performed by R software with wilcoxTest package (P<0.05 and log2 fold change >1) to illustrate miRNA expression profiles in the GEO database (GSE38290). (B) Volcano plot of DEGs. DEGs with log2 fold change >1.5 are shown in red. GSEA analysis was performed by Broad Institute website to show significantly enriched gene sets in melanoma mainly enriched in (C) cell growth, (D) regula- tion of MAPK cascade and (E) pathways in cancer. (F) The diagram of the PPI network. Co‑expression network of 11 genes. (G) Core protein histogram. The vertical coordinates are the gene names, and the horizontal coordinates are the number of adjacent genes, and the height represents the number of line connected genes. (H) mRNA expression level of PLCB2 in human melanoma cell lines was detected by RT‑PCR. GAPDH was used as a load control. Data are presented as the mean ± standard deviation. **P<0.01 vs. the <t>NHEM</t> cell group. PLCB2, phospholipase C β2; DEGs, differentially expressed genes; PPI‑protein‑protein interaction.
    Epidermal Melanocytic 105 25n Cell Line, supplied by Cell Applications Inc, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Image Search Results


    Human epidermal melanocytes HEM and human primary melanoma MM418-C1 monolayer 24 h after being exposed to 1000 Gy 90 kVp SBB (width 500 µm). Both cell types are treated with 1 m M AuNPs. The boundaries of the radiation fields are marked with orange lines. (A1) HEM immediately after exposure, (A2) 24 h, (A3) 48 h and (A4) 96 h after exposure. (B1) MM418-C1 immediately after exposure, (B1) 24 h, (B2) 48 h and (B4) 96 h after exposure.

    Journal: Journal of Synchrotron Radiation

    Article Title: Effects of synchrotron-based X-rays and gold nanoparticles on normal and cancer cell morphology and migration

    doi: 10.1107/S1600577522012024

    Figure Lengend Snippet: Human epidermal melanocytes HEM and human primary melanoma MM418-C1 monolayer 24 h after being exposed to 1000 Gy 90 kVp SBB (width 500 µm). Both cell types are treated with 1 m M AuNPs. The boundaries of the radiation fields are marked with orange lines. (A1) HEM immediately after exposure, (A2) 24 h, (A3) 48 h and (A4) 96 h after exposure. (B1) MM418-C1 immediately after exposure, (B1) 24 h, (B2) 48 h and (B4) 96 h after exposure.

    Article Snippet: Moshi Geso), and human colorectal adenocarcinoma SW48 (ATCC ® CCL-231 TM ; Manassas, VA, USA) – along with two different normal cell lines – human epidermal melanocytes HEM (ATCC ® PCS-200–013 TM ; Manassas, VA, USA) and human primary colon epithelial CCD841 CoN (ATCC ® CRL-1790 TM ; Manassas, VA, USA).

    Techniques:

    Figure 1. PLCB2 expression in malignant melanoma cell lines. (A) The heatmap analysis was performed by R software with wilcoxTest package (P<0.05 and log2 fold change >1) to illustrate miRNA expression profiles in the GEO database (GSE38290). (B) Volcano plot of DEGs. DEGs with log2 fold change >1.5 are shown in red. GSEA analysis was performed by Broad Institute website to show significantly enriched gene sets in melanoma mainly enriched in (C) cell growth, (D) regula- tion of MAPK cascade and (E) pathways in cancer. (F) The diagram of the PPI network. Co‑expression network of 11 genes. (G) Core protein histogram. The vertical coordinates are the gene names, and the horizontal coordinates are the number of adjacent genes, and the height represents the number of line connected genes. (H) mRNA expression level of PLCB2 in human melanoma cell lines was detected by RT‑PCR. GAPDH was used as a load control. Data are presented as the mean ± standard deviation. **P<0.01 vs. the NHEM cell group. PLCB2, phospholipase C β2; DEGs, differentially expressed genes; PPI‑protein‑protein interaction.

    Journal: Molecular medicine reports

    Article Title: Knockdown of PLCB2 expression reduces melanoma cell viability and promotes melanoma cell apoptosis by altering Ras/Raf/MAPK signals.

    doi: 10.3892/mmr.2019.10798

    Figure Lengend Snippet: Figure 1. PLCB2 expression in malignant melanoma cell lines. (A) The heatmap analysis was performed by R software with wilcoxTest package (P<0.05 and log2 fold change >1) to illustrate miRNA expression profiles in the GEO database (GSE38290). (B) Volcano plot of DEGs. DEGs with log2 fold change >1.5 are shown in red. GSEA analysis was performed by Broad Institute website to show significantly enriched gene sets in melanoma mainly enriched in (C) cell growth, (D) regula- tion of MAPK cascade and (E) pathways in cancer. (F) The diagram of the PPI network. Co‑expression network of 11 genes. (G) Core protein histogram. The vertical coordinates are the gene names, and the horizontal coordinates are the number of adjacent genes, and the height represents the number of line connected genes. (H) mRNA expression level of PLCB2 in human melanoma cell lines was detected by RT‑PCR. GAPDH was used as a load control. Data are presented as the mean ± standard deviation. **P<0.01 vs. the NHEM cell group. PLCB2, phospholipase C β2; DEGs, differentially expressed genes; PPI‑protein‑protein interaction.

    Article Snippet: The normal human epidermal melanocyte (nHeM) cell line was provided by cell applications inc. and cultured in M2 medium.

    Techniques: Expressing, Software, Control, Standard Deviation